Cannabidiol and human health

The most important and best-documented uses of cannabidiol in a wide range of scientific literature (for more details see the bibliography at the end of this note) on its positive effects on human health and its therapeutic potential are:

Cannabidiol as an anxiolytic and neuroleptic (in combination with Psychotherapy and Rehabilitation)

Sleep Disorders
Panic Attack Disorders
Obsessive Compulsive Disorders
Post-Traumatic Stress Disorders
Nutrition and Eating Disorders
Substance and Behavioural Dependence (especially Ludopathy)
Borderline Personality Disorder
Schizophrenia and Bipolar Psychosis

Cannabidiol as anti-inflammatory, painkiller and antispasmodic

Irritable bowel syndrome
Ulcerative rectocolitis and Crohn’s disease
Inflammatory and degenerative diseases of the osteoarticular system such as arthritis and arthrosis
Pre-menstrual syndrome
Muscle pain

Cannabidiol as an anti-ageing agent

In the preventive treatment of physiological cognitive and physical decline due to the
senescence process.
As an activator of cerebral metabolic processes and as a substance
Able to reduce neuro-inflammatory and neuro-degenerative processes
Neurocognitive disorders (Dementia)
Neurodevelopmental disorders (including Autism Spectrum Disorders and Attention Deficit Hyperactivity Disorders)
Parkinson’s disease and Parkinsonisms.





Cannabidiol in Cardiology/strong>

Cannabidiol has a positive effect on cardiovascular function, reducing systolic and diastolic values in the case of hypertension and slowing the heart rate when the heart rate is too high due to functional causes, mainly related to anxiety and stress. In addition, cannabidiol has a vasodilating effect, which helps to lower blood pressure and, above all, the perfusion of the various organs, particularly the brain.
Due to its powerful anti-inflammatory and antioxidant action, cannabidiol has a positive effect on atherosclerotic inflammation of the coronary arteries and the entire vascular system, promoting the healing of atheromatous lesions. The systematic intake of cannabidiol, in the case of atherosclerosis, integrated with the modification of harmful lifestyles, such as sedentariness and a qualitatively and quantitatively dysfunctional diet, contributes to the improvement of arterial disease. Cannabidiol also contributes to lower rates of circulating blood cholesterol, as shown by a 2013 study that analysed blood chemistry parameters of 4,652 participants on the effect of cannabis on metabolic systems, comparing non-users with users. Evidence from this study showed that regular consumers exhibited higher blood levels of high-density lipoprotein (HDL),

Cannabidiol, Appetite and Metabolism

When taken regularly, cannabidiol tends to stabilise and normalise eating behaviour, counteracting emotional eating and compulsive hunger. CBD also helps to lose weight or maintain a healthy weight by activating and improving mitochondrial function, thereby helping cells to utilise nutrients and convert them into energy. CBD intake also reduces the high insulin levels in the blood of people suffering from metabolic syndrome, which can be traced back to a diet too high in calories and carbohydrates and a sedentary lifestyle.

Cannabidiol in Dermatology

The strong anti-inflammatory, anti-itch and antibacterial activities of CBD suggest its topical use in dermatology.
Indeed, in dermatology, CBD is considered an excellent remedy for conditions such as dermatitis, acne and psoriasis. Medical devices in the form of CBD lotions and ointments for use in dermatology have recently become commercially available.


Cannabidiol in Dentistry

The anti-inflammatory, antibacterial and antioxidant properties of cannabidiol, together with the total absence of side effects, make it a possible remedy for a condition that affects millions of people, leading to the progressive loss of teeth with all the associated complications. A 2009 study at the Hebrew University of Jerusalem showed that topical application of CBD to the gums of patients suffering from periodontitis not only improved the inflammation and bacteria situation in the gum pockets, but also counteracted the reduction of alveolar bone tissue. In addition, the analgesic action of CBD reduces patients’ suffering, leading to a gradual improvement in chewing function.

Cannabidiol and Sexology

Cannabidiol, used in sexology, reduces performance anxiety and improves desire in both men and women. CBD also counteracts erectile dysfunction and premature ejaculation. CBD-based creams and lotions may also be useful in the integrated treatment of dyspareunia and vaginismus in women.

Cannabidiol in sports practice

The anti-inflammatory and antioxidant effect of cannabidiol proves invaluable in sporting activities, during which joint and muscle trauma or microtrauma can occur, as well as activating the production of free radicals and lactic acid, with negative metabolic consequences.